Lithium suppression of tau induces brain iron accumulation and neurodegeneration

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neurodegeneration with brain iron accumulation: an overview

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Neurodegeneration with Brain Iron Accumulation: An Overview

OBJECTIVE Neurodegeneration with brain iron accumulation (NBIA) is a group of neurodegenerative disorder with deposition of iron in the brain (mainly Basal Ganglia) leading to a progressive Parkinsonism, spasticity, dystonia, retinal degeneration, optic atrophy often accompanied by psychiatric manifestations and cognitive decline. 8 of the 10 genetically defined NBIA types are inherited as auto...

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ژورنال

عنوان ژورنال: Molecular Psychiatry

سال: 2016

ISSN: 1359-4184,1476-5578

DOI: 10.1038/mp.2016.96